The effective Hamiltonian for nonleptonic decays of strange, charm and beauty, involving the QCD corrections at short distances but with possible t-quark mass m
t > mw and a correction of the initial value for the renormalization group equations, is computed in the framework of the operator product expansion (OPE). The numerical results show that our calculation gives corrections in right direction for approaching to the Δ
1=1/2 rule and if using the latest experimental measurements on δ and ε'/ε for
system as input, the KM parameter ε
22 would be constrained in a reasonable region (2.5~22.5)×10
-3.