Understanding sequence effect in DNA bending elasticity by molecular dynamic simulations

Xiao-Wei Qiang,Hai-Long Dong,Kai-Xin Xiong,Wenbing Zhang,Zhi-Jie Tan

Table 2. The helical parameters and persistence length for DNAs with different sequencesa.

AA-TT AT-TA GENE Helical rise (Å) 3.34 ± 0.08 3.29 ± 0.08 3.33 ± 0.09 Helical twist (degree) 34.32 ± 0.83 34.94 ± 0.90 34.62 ± 1.10 Helical radius (Å) 10.17 ± 0.17 10.07 ± 0.16 10.14 ± 0.24 Major groove width (Å) 13.36 ± 0.84 12.34 ± 0.72 11.92 ± 0.64 Minor groove width (Å) 4.91 ± 0.45 5.36 ± 0.46 5.64 ± 0.45 Persistence length (nm)b 63 48 49