Modeling the roles of 14-3-3 Σ and Wip1 in p53 dynamics and programmed cell death*

Nan Liu(刘楠),Hongli Yang(杨红丽),Liangui Yang(杨联贵)

Figure 5. (a) Codimension 2 bifurcation diagram. The green line represents the Hopf bifurcation, and the black line represents the Fold bifurcation. The blue area indicates the bistable state; the white area indicates the monostable state; the yellow area indicates the oscillation. (b)–(d) are pseudo-phase plane, black dots represent stable fixed points, and black closed orbit represents stable limit cycle.