Balanced biosynthesis and trigger threshold resulting in a double adder mechanism of cell size control

Leilei Li

Figure 7. The Pearson correlation coefficients and slopes between various variables in the replication-centric picture. Each point stands for one cell in 20 000 consecutive cells after the system gets into the steady state. The red line is the linear fitting curve. (a) The increment between cell replication cycle Δif is uncorrelated with volume Si at replication initiation per origin. This result certificates the adder property in the replication-centric picture. (b) The correlation coefficient between the volume Si at the initial replication initiation per origin and the volume Sf at the final replication initiation per origin is 0.561 and the slope of the curve 1.123. (c) The time between replication initiation and cell division C + D is negatively correlated with Si. (d) The auto-correlation coefficient of Si is 0.562. If Donchie’s hypothesis is right, the value should be 0.